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Fischer rats exhibit maladaptive structural and molecular right ventricular remodelling in severe pulmonary hypertension: a genetically prone model for right heart failure

AIMS: The ability of the right ventricle (RV) to adapt to increased afterload is the major determinant of survival in patients with pulmonary hypertension (PH). In this study, we explored the effect of genetic background on RV adaptation and survival in a rat model of severe pulmonary arterial hyper...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Suen, Colin M, Chaudhary, Ketul R, Deng, Yupu, Jiang, Baohua, Stewart, Duncan J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432055/
https://ncbi.nlm.nih.gov/pubmed/30357319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy258
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