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Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences

The human CST (CTC1–STN1–TEN1) heterotrimeric complex plays roles in both telomere maintenance and DNA replication through its ability to interact with single-stranded DNA (ssDNA) of a variety of sequences. The precise sequence specificity required to execute these functions is unknown. Telomere-bin...

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Publicado en:Biochemistry
Main Authors: Hom, Robert A., Wuttke, Deborah S.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151266/
https://ncbi.nlm.nih.gov/pubmed/28726394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00584
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