Llwytho...

Kinetically Favored Platination of Adenine in the G-Rich Human Telomeric Repeat

[Image: see text] The interactions of PT-ACRAMTU, a cytotoxic platinum–acridine conjugate, with the human telomeric G-quadruplex have been studied using in-line high-performance liquid chromatography–mass spectrometry and footprinting assays. The conjugate reacts significantly faster with quadruplex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rao, Lu, Bierbach, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536596/
https://ncbi.nlm.nih.gov/pubmed/18047349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja077390a
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