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Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay

A restriction enzyme cleavage inhibition assay was designed to determine the rates of DNA platination by four non-cross-linking platinum–acridine agents represented by the formula [Pt(am(2))LCl](NO(3))(2), where am is a diamine nonleaving group and L is an acridine derived from the intercalator 1-[2...

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Detalhes bibliográficos
Main Authors: Choudhury, Jayati Roy, Rao, Lu, Bierbach, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049956/
https://ncbi.nlm.nih.gov/pubmed/21086002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-010-0733-z
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