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Telomeric Repeat Mutagenicity in Human Somatic Cells is Modulated by Repeat Orientation and G-Quadruplex Stability
Telomeres consisting of tandem guanine-rich repeats can form secondary DNA structures called G-quadruplexes that represent potential targets for DNA repair enzymes. While G-quadruplexes interfere with DNA synthesis in vitro, the impact of G-quadruplex formation on telomeric repeat replication in hum...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988439/ https://ncbi.nlm.nih.gov/pubmed/20800555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.07.014 |
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