Telomeric Repeat Mutagenicity in Human Somatic Cells is Modulated by Repeat Orientation and G-Quadruplex Stability

Telomeres consisting of tandem guanine-rich repeats can form secondary DNA structures called G-quadruplexes that represent potential targets for DNA repair enzymes. While G-quadruplexes interfere with DNA synthesis in vitro, the impact of G-quadruplex formation on telomeric repeat replication in hum...

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Bibliografski detalji
Glavni autori: Damerla, Rama Rao, Knickelbein, Kelly E., Kepchia, Devin, Jackson, Abbe, Armitage, Bruce A., Eckert, Kristin A., Opresko, Patricia L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988439/
https://ncbi.nlm.nih.gov/pubmed/20800555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.07.014
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