Environmental Enrichment and Social Isolation Mediate Neuroplasticity of Medium Spiny Neurons through the GSK3 Pathway

Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na(+) channel Nav1.6 as regulators of neuroplasticity induced by environmentall...

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Publicado no:Cell Rep
Main Authors: Scala, Federico, Nenov, Miroslav N., Crofton, Elizabeth J., Singh, Aditya K., Folorunso, Oluwarotimi, Zhang, Yafang, Chesson, Brent C., Wildburger, Norelle C., James, Thomas F., Alshammari, Musaad A., Alshammari, Tahani K., Elfrink, Hannah, Grassi, Claudio, Kasper, James M., Smith, Ashley E., Hommel, Jonathan D., Lichti, Cheryl F., Rudra, Jai S., D’Ascenzo, Marcello, Green, Thomas A., Laezza, Fernanda
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150488/
https://ncbi.nlm.nih.gov/pubmed/29642012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.062
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