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An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells

Increasing evidence suggests that an enriched environment (EE) ameliorates cognitive impairment by promoting repair of brain damage. However, the mechanisms by which this occurs have not been determined. To address this issue, we investigated whether an EE enhanced the capability of endogenous bone...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kubota, Kenta, Nakano, Masako, Kobayashi, Eiji, Mizue, Yuka, Chikenji, Takako, Otani, Miho, Nagaishi, Kanna, Fujimiya, Mineko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150479/
https://ncbi.nlm.nih.gov/pubmed/30240403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204252
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