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Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus

Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β and tau. We previously reported that administration of bone marrow mesenchymal stem cells (BM-MSCs) ameliorates diabetes-induced cognitive impairment by transferring exosomes derived from these cells into astrocytes. Here, we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakano, Masako, Kubota, Kenta, Kobayashi, Eiji, Chikenji, Takako S., Saito, Yuki, Konari, Naoto, Fujimiya, Mineko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330036/
https://ncbi.nlm.nih.gov/pubmed/32612165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67460-1
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