An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells

Increasing evidence suggests that an enriched environment (EE) ameliorates cognitive impairment by promoting repair of brain damage. However, the mechanisms by which this occurs have not been determined. To address this issue, we investigated whether an EE enhanced the capability of endogenous bone...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kubota, Kenta, Nakano, Masako, Kobayashi, Eiji, Mizue, Yuka, Chikenji, Takako, Otani, Miho, Nagaishi, Kanna, Fujimiya, Mineko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150479/
https://ncbi.nlm.nih.gov/pubmed/30240403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204252
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