Activated forms of astrocytes with higher GLT-1 expression are associated with cognitive normal subjects with Alzheimer pathology in human brain

Although the cognitive impairment in Alzheimer’s disease (AD) is believed to be caused by amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs), several postmortem studies have reported cognitive normal subjects with AD brain pathology. As the mechanism underlying these discrepancies has not bee...

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Pubblicato in:Sci Rep
Autori principali: Kobayashi, Eiji, Nakano, Masako, Kubota, Kenta, Himuro, Nobuaki, Mizoguchi, Shougo, Chikenji, Takako, Otani, Miho, Mizue, Yuka, Nagaishi, Kanna, Fujimiya, Mineko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786045/
https://ncbi.nlm.nih.gov/pubmed/29374250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19442-7
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