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Asparagine, a critical limiting metabolite during glutamine starvation
A challenge of targeting glutamine metabolism in cancer is that tumor cells develop various strategies to adapt to glutamine limitation. We found that asparagine plays a critical role in supporting protein synthesis during glutamine starvation, highlighting a possible approach to optimize the therap...
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| Publicado en: | Mol Cell Oncol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149945/ https://ncbi.nlm.nih.gov/pubmed/30250896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1441633 |
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