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Asparagine Is a Critical Limiting Metabolite for Vaccinia Virus Protein Synthesis during Glutamine Deprivation

Viruses actively interact with host metabolism because viral replication relies on host cells to provide nutrients and energy. Vaccinia virus (VACV; the prototype poxvirus) prefers glutamine to glucose for efficient replication to the extent that VACV replication is hindered in glutamine-free medium...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pant, Anil, Cao, Shuai, Yang, Zhilong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580962/
https://ncbi.nlm.nih.gov/pubmed/30996100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01834-18
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