EnABLing Cathepsin-Driven Melanoma Metastasis

Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating pro-invasive proteases. We reported that ABL kinases induce cathepsin secretion and subsequent metastasis by activating ETS1, SP1, and RELA pathways,...

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Bibliographic Details
Published in:	Mol Cell Oncol
Main Authors:	Tripathi, Rakshamani, Plattner, Rina
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2018
Subjects:	Author's Views
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6149941/ https://ncbi.nlm.nih.gov/pubmed/30250913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1458016
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EnABLing Cathepsin-Driven Melanoma Metastasis

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