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EnABLing Cathepsin-Driven Melanoma Metastasis
Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating pro-invasive proteases. We reported that ABL kinases induce cathepsin secretion and subsequent metastasis by activating ETS1, SP1, and RELA pathways,...
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| Vydáno v: | Mol Cell Oncol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149941/ https://ncbi.nlm.nih.gov/pubmed/30250913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1458016 |
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