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Custom made inclusion bodies: impact of classical process parameters and physiological parameters on inclusion body quality attributes
BACKGROUND: The bacterium E. coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly. In many cases the formation of inclusion bodies (IBs), protein aggregates inside of the cyt...
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| Publicado no: | Microb Cell Fact |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148765/ https://ncbi.nlm.nih.gov/pubmed/30236107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-0997-5 |
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