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Boosting Recombinant Inclusion Body Production—From Classical Fed-Batch Approach to Continuous Cultivation

State of the art microbial recombinant protein production is regularly performed in fed-batch based cultivations. However, these cultivations suffer from highly time-dependent changes in productivity and product quality, leading to high variations in the downstream process. Continuous biomanufacturi...

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Podrobná bibliografie
Vydáno v:Front Bioeng Biotechnol
Hlavní autoři: Kopp, Julian, Kolkmann, Anna-Maria, Veleenturf, Patrick Gwen, Spadiut, Oliver, Herwig, Christoph, Slouka, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834550/
https://ncbi.nlm.nih.gov/pubmed/31737617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00297
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