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Synthesis and biological evaluation of novel 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors
A novel series of sulfonamide derivatives, coupled with a salicylamide scaffold, was designed and synthesized. The structures of the synthesized compounds were established using (1)H NMR, (13)C NMR and high-resolution mass spectroscopy. The synthesized compounds were tested in vitro against five typ...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148682/ https://ncbi.nlm.nih.gov/pubmed/30288225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00214b |
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