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Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

Elucidating the structural basis of antibody (Ab) gene usage and affinity maturation of vaccine-induced Abs can inform the design of immunogens for inducing desired Ab responses in HIV vaccine development. Analyses of monoclonal Abs (MAbs) encoded by the same immunoglobulin genes at different stages...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Chan, Kun-Wei, Pan, Ruimin, Costa, Matthew, Gorny, Miroslaw K., Wang, Shixia, Lu, Shan, Kong, Xiang-Peng
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146712/
https://ncbi.nlm.nih.gov/pubmed/29997214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00641-18
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