Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding

The fourth conserved region (C4) in the HIV-1 envelope glycoprotein (Env) gp120 is a structural element that is important for its function, as it binds to both the receptor CD4 and the co-receptor CCR5/CXCR4. It has long been known that this region is highly immunogenic and that it harbors B-cell as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Pan, Ruimin, Chen, Yuxin, Vaine, Michael, Hu, Guangnan, Wang, Shixia, Lu, Shan, Kong, Xiang-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522616/
https://ncbi.nlm.nih.gov/pubmed/26251831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2015.44
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados