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Probing Zika Virus Neutralization Determinants with Glycoprotein Mutants Bearing Linear Epitope Insertions

Zika virus (ZIKV) glycoproteins are the primary target of the humoral immune response. In this study, we explored the capacity of these glycoproteins to tolerate insertion of linear epitope sequences and the potential of antibodies that bind these epitopes to inhibit infection. We first created a pa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chambers, Matthew T., Schwarz, Megan C., Sourisseau, Marion, Gray, Essanna S., Evans, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146680/
https://ncbi.nlm.nih.gov/pubmed/29976678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-18
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