Prediction and Identification of a Permissive Epitope Insertion Site in the Vesicular Stomatitis Virus Glycoprotein

We developed a rational approach to identify a site in the vesicular stomatitis virus (VSV) glycoprotein (G) that is exposed on the protein surface and tolerant of foreign epitope insertion. The foreign epitope inserted was the six-amino-acid sequence ELDKWA, a sequence in a neutralizing epitope fro...

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Bibliographic Details
Published in:J Virol
Main Authors: Schlehuber, Lisa D., Rose, John K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15113889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.10.5079-5087.2004
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