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Probing Zika Virus Neutralization Determinants with Glycoprotein Mutants Bearing Linear Epitope Insertions

Zika virus (ZIKV) glycoproteins are the primary target of the humoral immune response. In this study, we explored the capacity of these glycoproteins to tolerate insertion of linear epitope sequences and the potential of antibodies that bind these epitopes to inhibit infection. We first created a pa...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Chambers, Matthew T., Schwarz, Megan C., Sourisseau, Marion, Gray, Essanna S., Evans, Matthew J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146680/
https://ncbi.nlm.nih.gov/pubmed/29976678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-18
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