Probing Zika Virus Neutralization Determinants with Glycoprotein Mutants Bearing Linear Epitope Insertions

Zika virus (ZIKV) glycoproteins are the primary target of the humoral immune response. In this study, we explored the capacity of these glycoproteins to tolerate insertion of linear epitope sequences and the potential of antibodies that bind these epitopes to inhibit infection. We first created a pa...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Chambers, Matthew T., Schwarz, Megan C., Sourisseau, Marion, Gray, Essanna S., Evans, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146680/
https://ncbi.nlm.nih.gov/pubmed/29976678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-18
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