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Denervation-activated STAT3-IL6 signaling in fibro-adipogenic progenitors promotes myofibers atrophy and fibrosis
Fibro-Adipogenic Progenitors (FAPs) are typically activated in response to muscle injury, and establish functional interactions with inflammatory and muscle stem cells (MuSCs) to promote muscle repair. We found that denervation causes progressive accumulation of FAPs, without concomitant infiltratio...
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| 出版年: | Nat Cell Biol |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6145844/ https://ncbi.nlm.nih.gov/pubmed/30050118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0151-y |
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