Denervation-activated STAT3-IL6 signaling in fibro-adipogenic progenitors promotes myofibers atrophy and fibrosis

Fibro-Adipogenic Progenitors (FAPs) are typically activated in response to muscle injury, and establish functional interactions with inflammatory and muscle stem cells (MuSCs) to promote muscle repair. We found that denervation causes progressive accumulation of FAPs, without concomitant infiltratio...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Cell Biol
Egile Nagusiak: Madaro, Luca, Passafaro, Magda, Sala, David, Etxaniz, Usue, Lugarini, Francesca, Proietti, Daisy, Alfonsi, Maria Vittoria, Nicoletti, Chiara, Gatto, Sole, De Bardi, Marco, Rojas-García, Ricardo, Giordani, Lorenzo, Marinelli, Sara, Pagliarini, Vittoria, Sette, Claudio, Sacco, Alessandra, Puri, Pier Lorenzo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145844/
https://ncbi.nlm.nih.gov/pubmed/30050118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0151-y
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