ロード中...
Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis
Genome sequencing studies have revealed a number of cancer-associated mutations in the telomerebinding factor POT1. Here, we show that when combined with p53 deficiency, depletion of murine POT1a in common lymphoid progenitor cells fosters genetic instability, accelerates the onset, and increases th...
保存先:
| 出版年: | Cell Rep |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6145145/ https://ncbi.nlm.nih.gov/pubmed/27239034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.008 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|