Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB

Most RecQ DNA helicases share a conserved domain arrangement that mediates their activities in genomic stability. This arrangement comprises a helicase motor domain, a RecQ C-terminal (RecQ-C) region including a winged-helix (WH) domain, and a ‘Helicase and RNase D C-terminal’ (HRDC) domain. Single-...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bagchi, Debjani, Manosas, Maria, Zhang, Weiting, Manthei, Kelly A, Hodeib, Samar, Ducos, Bertrand, Keck, James L, Croquette, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144805/
https://ncbi.nlm.nih.gov/pubmed/30053104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky647
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