Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases

RecQ helicases unwind remarkably diverse DNA structures as key components of many cellular processes. How RecQ enzymes accommodate different substrates in a unified mechanism that couples ATP hydrolysis to DNA unwinding is unknown. Here, the X-ray crystal structure of the Cronobacter sakazakii RecQ...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Manthei, Kelly A., Hill, Morgan C., Burke, Jordan E., Butcher, Samuel E., Keck, James L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394303/
https://ncbi.nlm.nih.gov/pubmed/25831501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416746112
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