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Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases

RecQ helicases unwind remarkably diverse DNA structures as key components of many cellular processes. How RecQ enzymes accommodate different substrates in a unified mechanism that couples ATP hydrolysis to DNA unwinding is unknown. Here, the X-ray crystal structure of the Cronobacter sakazakii RecQ...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Manthei, Kelly A., Hill, Morgan C., Burke, Jordan E., Butcher, Samuel E., Keck, James L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394303/
https://ncbi.nlm.nih.gov/pubmed/25831501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416746112
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