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Neisseria gonorrhoeae RecQ Helicase HRDC Domains Are Essential for Efficient Binding and Unwinding of the pilE Guanine Quartet Structure Required for Pilin Antigenic Variation

The strict human pathogen Neisseria gonorrhoeae utilizes homologous recombination to antigenically vary the pilus, thus evading the host immune response. High-frequency gene conversion reactions between many silent pilin loci and the expressed pilin locus (pilE) allow for numerous pilus variants per...

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Detalles Bibliográficos
Main Authors: Cahoon, Laty A., Manthei, Kelly A., Rotman, Ella, Keck, James L., Seifert, H. Steven
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650551/
https://ncbi.nlm.nih.gov/pubmed/23475972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02217-12
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