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The RecA-binding pilE G4 Sequence Essential for Pilin Antigenic Variation forms Parallel-stranded Monomeric and 5´-End Stacked Dimeric G-quadruplexes

Neisseria gonorrhoeae is an obligate human pathogen that can escape immune surveillance through antigenic variation of surface structures such as pili. A G-quadruplex-forming (G4) sequence (5´-G(3)TG(3)TTG(3)TG(3)) located upstream of the N. gonorrhoeae pilin expression locus (pilE) is necessary for...

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Detalhes bibliográficos
Main Authors: Kuryavyi, Vitaly, Cahoon, Laty A., Seifert, H. Steven, Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845372/
https://ncbi.nlm.nih.gov/pubmed/23085077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.09.013
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