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The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
DNA helicases of the RecQ family are conserved among the three domains of life and play essential roles in genome maintenance. Mutations in several human RecQ helicases lead to diseases that are marked by cancer predisposition. The Saccharomyces cerevisiae RecQ helicase Sgs1 is orthologous to human...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511845/ https://ncbi.nlm.nih.gov/pubmed/30916344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz186 |
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