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The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments

DNA helicases of the RecQ family are conserved among the three domains of life and play essential roles in genome maintenance. Mutations in several human RecQ helicases lead to diseases that are marked by cancer predisposition. The Saccharomyces cerevisiae RecQ helicase Sgs1 is orthologous to human...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Crickard, J Brooks, Xue, Chaoyou, Wang, Weibin, Kwon, Youngho, Sung, Patrick, Greene, Eric C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511845/
https://ncbi.nlm.nih.gov/pubmed/30916344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz186
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