BTC1.04 Genomic profiling of IDH-wildtype and IDH-mutant initial and matched recurrent glioblastomas reveals clinically actionable mutations (e.g. BRCA1/2) and resistance signatures

BACKGROUND: Glioblastomas account for 90% of all adult brain tumours. Patient survival remains low because treatments are ineffective against this lethal disease. Understanding the genes and pathways altered in subtypes is necessary for therapeutic intervention. MATERIAL AND METHODS: Tumours from 41...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: McInerney, C E, Ellis, H P, Schrimpf, D, Sahm, F, Stupnikov, A, Wadsley, M, Wragg, C, White, P, Prise, K M, McArt, D G, Kurian, K M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Oral Presentations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144622/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares