Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS)

INTRODUCTION: Spinal and bulbar muscular atrophy (SBMA) is a slowly progressive neuromuscular disease. Cold exposure often leads to worsening of motor symptoms including paresis. Although mexiletine hydrochloride administration has been shown to be effective for the treatment of several muscular dis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMJ Open
Hauptverfasser: Yamada, Shinichiro, Hashizume, Atsushi, Hijikata, Yasuhiro, Inagaki, Tomonori, Ito, Daisuke, Kinoshita, Fumie, Nakatochi, Masahiro, Kobayashi, Yumiko, Hirakawa, Akihiro, Nakamura, Tomohiko, Katsuno, Masahisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2018
Schlagworte:
Neurology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144396/
https://ncbi.nlm.nih.gov/pubmed/30206090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-023041
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge