Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS)

INTRODUCTION: Spinal and bulbar muscular atrophy (SBMA) is a slowly progressive neuromuscular disease. Cold exposure often leads to worsening of motor symptoms including paresis. Although mexiletine hydrochloride administration has been shown to be effective for the treatment of several muscular dis...

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Detaylı Bibliyografya
Yayımlandı:BMJ Open
Asıl Yazarlar: Yamada, Shinichiro, Hashizume, Atsushi, Hijikata, Yasuhiro, Inagaki, Tomonori, Ito, Daisuke, Kinoshita, Fumie, Nakatochi, Masahiro, Kobayashi, Yumiko, Hirakawa, Akihiro, Nakamura, Tomohiko, Katsuno, Masahisa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2018
Konular:
Neurology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144396/
https://ncbi.nlm.nih.gov/pubmed/30206090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-023041
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