Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS)

INTRODUCTION: Spinal and bulbar muscular atrophy (SBMA) is a slowly progressive neuromuscular disease. Cold exposure often leads to worsening of motor symptoms including paresis. Although mexiletine hydrochloride administration has been shown to be effective for the treatment of several muscular dis...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMJ Open
Κύριοι συγγραφείς: Yamada, Shinichiro, Hashizume, Atsushi, Hijikata, Yasuhiro, Inagaki, Tomonori, Ito, Daisuke, Kinoshita, Fumie, Nakatochi, Masahiro, Kobayashi, Yumiko, Hirakawa, Akihiro, Nakamura, Tomohiko, Katsuno, Masahisa
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BMJ Publishing Group 2018
Θέματα:
Neurology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144396/
https://ncbi.nlm.nih.gov/pubmed/30206090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-023041
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