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P04.70 Anti-Notch1 treatment suppressed the invasion, self-renewal and tumor growth of glioma initiating cells mediated by chemokine system CXCL12/CXCR4

BACKGROUND: Glioma initiating cells (GICs), also known as glioma stem cells (GSCs), play an important role in the progression and recurrence of glioblastoma multiforme (GBM) due to their potential for self-renewal, multiple differentiation and tumor initiation. In the recent years, Notch1 has been f...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Yi, L, Yang, X
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144137/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.304
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