Notch1 signaling pathway promotes invasion, self-renewal and growth of glioma initiating cells via modulating chemokine system CXCL12/CXCR4

BACKGROUND: Glioma initiating cells (GICs), also known as glioma stem cells (GSCs), play an important role in the progression and recurrence of glioblastoma multiforme (GBM) due to their potential for self-renewal, multiple differentiation and tumor initiation. In the recent years, Notch1 has been f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Yi, Li, Zhou, Xingchen, Li, Tao, Liu, Peidong, Hai, Long, Tong, Luqing, Ma, Haiwen, Tao, Zhennan, Xie, Yang, Zhang, Chen, Yu, Shengping, Yang, Xuejun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683584/
https://ncbi.nlm.nih.gov/pubmed/31382985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1319-4
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