SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH(2)-terminal kinase

c-Jun NH(2)-terminal kinases (JNKs) are responsive to stress stimuli and their activation regulate key cellular functions, including cell survival, growth, differentiation and aging. Previous studies demonstrate that activation of JNK requires dual phosphorylation by the mitogen-activated protein ki...

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Pubblicato in:Cell Death Differ
Autori principali: Sarikhani, Mohsen, Mishra, Sneha, Desingu, Perumal Arumugam, Kotyada, Chaithanya, Wolfgeher, Donald, Gupta, Mahesh P., Singh, Mahavir, Sundaresan, Nagalingam R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143545/
https://ncbi.nlm.nih.gov/pubmed/29449643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0069-8
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