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SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation
Glycogen synthase kinase 3 (GSK3) is a critical regulator of diverse cellular functions involved in the maintenance of structure and function. Enzymatic activity of GSK3 is inhibited by N-terminal serine phosphorylation. However, alternate post-translational mechanism(s) responsible for GSK3 inactiv...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860870/ https://ncbi.nlm.nih.gov/pubmed/29504933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32952 |
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