SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH(2)-terminal kinase

c-Jun NH(2)-terminal kinases (JNKs) are responsive to stress stimuli and their activation regulate key cellular functions, including cell survival, growth, differentiation and aging. Previous studies demonstrate that activation of JNK requires dual phosphorylation by the mitogen-activated protein ki...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Sarikhani, Mohsen, Mishra, Sneha, Desingu, Perumal Arumugam, Kotyada, Chaithanya, Wolfgeher, Donald, Gupta, Mahesh P., Singh, Mahavir, Sundaresan, Nagalingam R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143545/
https://ncbi.nlm.nih.gov/pubmed/29449643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0069-8
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