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Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma

INTRODUCTION: Novel approaches to treat malignant brain tumors are necessary since these neoplasms still display an unfavorable prognosis. AREAS COVERED: In this review, the authors summarize and analyze recent preclinical data that suggest that targeting intrinsic apoptosis may be a suitable strate...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Discov
Main Authors: Karpel-Massler, Georg, Ishida, Chiaki Tsuge, Zhang, Yiru, Halatsch, Marc-Eric, Westhoff, M.-Andrew, Siegelin, Markus D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143391/
https://ncbi.nlm.nih.gov/pubmed/28712306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2017.1356286
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