Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells

It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs). An in-depth understanding of the mechanisms of HSC necroptosis might provide a new therapeutic strategy for...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Jia, Yan, Wang, Feixia, Guo, Qin, Li, Mengmeng, Wang, Ling, Zhang, Zili, Jiang, Shuoyi, Jin, Huanhuan, Chen, Anping, Tan, Shanzhong, Zhang, Feng, Shao, Jiangjuan, Zheng, Shizhong
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142373/
https://ncbi.nlm.nih.gov/pubmed/30237126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.007
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