Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells

It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs). An in-depth understanding of the mechanisms of HSC necroptosis might provide a new therapeutic strategy for...

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Detalles Bibliográficos
Publicado en:Redox Biol
Autores principales: Jia, Yan, Wang, Feixia, Guo, Qin, Li, Mengmeng, Wang, Ling, Zhang, Zili, Jiang, Shuoyi, Jin, Huanhuan, Chen, Anping, Tan, Shanzhong, Zhang, Feng, Shao, Jiangjuan, Zheng, Shizhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142373/
https://ncbi.nlm.nih.gov/pubmed/30237126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.007
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