Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells

It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs). An in-depth understanding of the mechanisms of HSC necroptosis might provide a new therapeutic strategy for...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Jia, Yan, Wang, Feixia, Guo, Qin, Li, Mengmeng, Wang, Ling, Zhang, Zili, Jiang, Shuoyi, Jin, Huanhuan, Chen, Anping, Tan, Shanzhong, Zhang, Feng, Shao, Jiangjuan, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142373/
https://ncbi.nlm.nih.gov/pubmed/30237126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.007
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