Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro

Acute-on-chronic liver failure (ACLF) is described as a characteristic of acute jaundice and coagulation dysfunction. Effective treatments for ACLF are unavailable and hence are urgently required. We aimed to define the effect of Yi-Qi-Jian-Pi Formula (YQJPF) on liver injury and further examine the...

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Vydáno v:Front Pharmacol
Hlavní autoři: Wang, Feixia, Tang, Li, Liang, Baoyu, Jin, Chun, Gao, Liyuan, Li, Yujia, Li, Zhanghao, Shao, Jiangjuan, Zhang, Zili, Tan, Shanzhong, Zhang, Feng, Zheng, Shizhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102982/
https://ncbi.nlm.nih.gov/pubmed/33967802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.658811
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