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Cre-Recombinase Dependent Germline Deletion of a Conditional Allele in the Rgs9cre Mouse Line
Cre-LoxP conditional knockout animals have become a prominent tool to understand gene function in discrete cell-types and neural circuits. However, this technology has significant limitations including off target cre-dependent recombination. The Rgs9cre strain has been used to generate a conditional...
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| 發表在: | Front Neural Circuits |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6141680/ https://ncbi.nlm.nih.gov/pubmed/30254571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2018.00068 |
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