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Cre-Recombinase Dependent Germline Deletion of a Conditional Allele in the Rgs9cre Mouse Line

Cre-LoxP conditional knockout animals have become a prominent tool to understand gene function in discrete cell-types and neural circuits. However, this technology has significant limitations including off target cre-dependent recombination. The Rgs9cre strain has been used to generate a conditional...

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Bibliografische gegevens
Gepubliceerd in:Front Neural Circuits
Hoofdauteur: Liput, Daniel J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141680/
https://ncbi.nlm.nih.gov/pubmed/30254571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2018.00068
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