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Conditional Wwox Deletion in Mouse Mammary Gland by Means of Two Cre Recombinase Approaches

Loss of WWOX expression has been reported in many different cancers including breast cancer. Elucidating the function of this gene in adult tissues has not been possible with full Wwox knockout models. Here we characterize the first conditional models of Wwox ablation in mouse mammary epithelium uti...

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Detalhes bibliográficos
Main Authors: Ferguson, Brent W., Gao, Xinsheng, Kil, Hyunsuk, Lee, Jaeho, Benavides, Fernando, Abba, Martin C., Aldaz, C. Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344920/
https://ncbi.nlm.nih.gov/pubmed/22574198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036618
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