Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms such as certain B cell lymphomas and multiple myelo...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: McBride, Kevin M., Kil, Hyunsuk, Mu, Yunxiang, Plummer, Joshua B., Lee, Jaeho, Zelazowski, Maciej J., Sebastian, Manu, Abba, Martin C., Aldaz, C. Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593956/
https://ncbi.nlm.nih.gov/pubmed/31275852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00517
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