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Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation
Th17 cells favor glycolytic metabolism, and pyruvate dehydrogenase (PDH) is the key bifurcation enzyme, which in its active dephosphorylated form advances the oxidative phosphorylation from glycolytic pathway. The transcriptional factor, inducible cAMP early repressor/cAMP response element modulator...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140513/ https://ncbi.nlm.nih.gov/pubmed/30150402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805717115 |
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