Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation

Th17 cells favor glycolytic metabolism, and pyruvate dehydrogenase (PDH) is the key bifurcation enzyme, which in its active dephosphorylated form advances the oxidative phosphorylation from glycolytic pathway. The transcriptional factor, inducible cAMP early repressor/cAMP response element modulator...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Kono, Michihito, Yoshida, Nobuya, Maeda, Kayaho, Skinner, Nicole E., Pan, Wenliang, Kyttaris, Vasileios C., Tsokos, Maria G., Tsokos, George C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140513/
https://ncbi.nlm.nih.gov/pubmed/30150402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805717115
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