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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells

Glutaminolysis is a well-known source of energy for effector T cells but its contribution to each T cell subset and the mechanisms which are responsible for the control of involved metabolic enzymes are not fully understood. We report that Th17 but not Th1, Th2, or Treg cell induction in vitro depen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kono, Michihito, Yoshida, Nobuya, Maeda, Kayaho, Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877961/
https://ncbi.nlm.nih.gov/pubmed/29463741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714717115
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