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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells
Glutaminolysis is a well-known source of energy for effector T cells but its contribution to each T cell subset and the mechanisms which are responsible for the control of involved metabolic enzymes are not fully understood. We report that Th17 but not Th1, Th2, or Treg cell induction in vitro depen...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877961/ https://ncbi.nlm.nih.gov/pubmed/29463741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714717115 |
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