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ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-β1

The a disintegrin and metalloproteinase (ADAM) family of proteinases alter the extracellular environment and are involved in the development of T cells and autoimmunity. The role of ADAM family members in Th17 cell differentiation is unknown. We identified ADAM9 to be specifically expressed and to p...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Umeda, Masataka, Yoshida, Nobuya, Hisada, Ryo, Burbano, Catalina, Orite, Seo Yeon K., Kono, Michihito, Kyttaris, Vasileios C., Krishfield, Suzanne, Owen, Caroline A., Tsokos, George C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106302/
https://ncbi.nlm.nih.gov/pubmed/33911034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023230118
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